Siskiyou County /ˈsɪskjuː/ SISS-kew is a county located in the far northernmost part of the U.S. state of California, in the Shasta Cascade region on the Oregon border. Yreka is the county seat. Because of its substantial natural beauty, outdoor recreation opportunities, and Gold Rush era history, it is an important tourist destination within the state. The population was 44,900 at the 2010 census.
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